DL-homatropine hydrobromide
Structural formula
| Physical competition number | 0151 |
|---|---|
| Molecular formula | C16H22BrNO3 |
| Molecular weight | 356.3 |
| label |
homatropine hydrobromide, Alpha-Hydroxyphenylacetate Hydrobromide, 8-Methyl-8-azabicyclo[3.2.1]octan-3-ol, Phenyl glycoltropine hydrobromide, Tropine mandelate hydrobromide, anticholinergics, Mydriatic medicine |
Numbering system
CAS number:51-56-9
MDL number:MFCD00012676
EINECS number:200-105-3
RTECS number:YM5602000
BRN number:None
PubChem ID:None
Physical property data
1. Properties: white orthorhombic bipyramidal prism crystal or powder. Odorless. Very bitter taste.
2. Density (g/mL, 25/4℃): Undetermined
3. Relative vapor density (g/mL, air=1): Undetermined
4. Melting point (ºC): 212 (partially decomposed)
5. Boiling point (ºC, normal pressure): Undetermined
6. Boiling point (ºC, 5.2kPa ): Not determined
7. Refractive index: Not determined
8. Flash point (ºC): Not determined
9. Specific rotation (º) : Undetermined
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (kPa, 25ºC): Undetermined
12. Saturated vapor pressure (kPa, 60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Log value of oil-water (octanol/water) partition coefficient: Undetermined
17. Explosion Upper limit (%, V/V): Undetermined
18. Lower explosion limit (%, V/V): Undetermined
19. Solubility: 1g product dissolves in 6ml water , 40ml ethanol, 420ml chloroform, insoluble in ether. Its solubility decreases with increasing temperature.
Toxicological data
1. Acute toxicity:; rat abdominal LD50: 154mg/kg; mouse intravenous LD50: 107mg/kg
Ecological data
None
Molecular structure data
1. Molar refractive index: 76.15
2. Molar volume (cm3/mol): 226.1
3. Isotonic specific volume (90.2K ): 606.0
4. Surface tension (dyne/cm): 51.5
5. Polarizability (10-24cm3): 30.19
Compute chemical data
None
Properties and stability
None
Storage method
Should be sealed, dry and protected from light.
Synthesis method
None
Purpose
This product is a synthetic anticholinergic drug that blocks acetylcholine and paralyzes the pupillary sphincter and cycloplegic muscles, causing mydriasis and accommodation paralysis. It is faster and weaker than atropine and is suitable for eye examinations. and optometry.
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